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API (Active Pharmaceutical Ingredient)
 
 Allopurinol
Active Pharmaceutical Ingredient
Allopurinol
Chemical Name
1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
CAS No.
315-30-0
Molecular Formula
C5H4N4O
Molecular Weight
136.1
Pharmacopoeial Compliance
Ph.Eur. / BP / USP
Description
White or almost white powder, very slightly soluble in water and in ethanol (96%), dissolves in dilute solution of alkali hydroxides
Therapeutic Category
Anti-urolithic (Uricosuric Agent)
 Amodiaquine Base
Active Pharmaceutical Ingredient
Amodiaquine Base
Chemical Name
4-[(7-Chloro-4-quinolinyl)amino]-α-[(diethylamino)-o-cresol
CAS No.
86-42-0
Molecular Formula
C20H22ClN3O
Molecular Weight
355.86
Pharmacopoeial Compliance
USP
Description
Very pale yellow to light tan yellow; odorless powder. Practically insoluble in water, sparingly soluble in 1N hydrochloric acid slightly soluble in alcohol.
Therapeutic Category
Anti-Malarial
 Amodiaquine HCl
Active Pharmaceutical Ingredient
Amodiaquine HCl
Chemical Name
4-[(7-chloro-4-quinolyl)amino]- α (diethylamino)-o-cresol dihydrochloride dihydrate
CAS No.
6398-98-7
Molecular Formula
C20H22ClN3O.2HCl.2H2O
Molecular Weight
464.81
Pharmacopoeial Compliance
USP / IP / IHT
Description
Yellow crystalline powder, is odorless and has a bitter taste. Soluble in water; sparingly soluble in alcohol; very slightly soluble in benzene; in chloroform and in ether.
Therapeutic Category
Anti-Malarial
 Artemether
Active Pharmaceutical Ingredient
Artemether
Chemical Name
3R,5aS,6R,8aS,9R,10S,12R,12aR) – Decahydro - 10 -methoxy-3,6,9 -trimethyl-3,12 -epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
CAS No.
71963-77-4
Molecular Formula
C16H26O5
Molecular Weight
298.4
Pharmacopoeial Compliance
Ph.Int. / IP
Description
A white crystalline powder. Practically insoluble in water, very soluble in Dichloromethane & in Acetone, freely soluble in Ethyl acetate & in dehydrated Ethanol. Melting range - 86°C to 90°C
Therapeutic Category
Anti-Malarial
 Artesunate
Active Pharmaceutical Ingredient
Artesunate
Chemical Name
[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin -10-ol]-hydrogen succinate
CAS No.
182824-33-5
Molecular Formula
C19H28O8
Molecular Weight
384.4
Pharmacopoeial Compliance
Ph.Int.
Description
A fine, white crystalline powder. Very slightly soluble in water; very soluble in dichloromethane, freely soluble in ethanol (~750 g/l) & acetone.
Therapeutic Category
Anti-Malarial
 Bisoprolol fumarate
Active Pharmaceutical Ingredient
Bisoprolol fumarate
Chemical Name
2-propanol, 1-[4-[[2-(1-Methylethoxy)ethoxy]methyl] phenoxy]-3-[(1-methylethyl)amino]-, (±) (E)-2-butenedioate (2:1) (salt)
CAS No.
104344-23-2
Molecular Formula
(C18H31NO4)2.C4H4O4
Molecular Weight
766.96
Pharmacopoeial Compliance
Ph.Eur. / BP / USP
Description
white or almost white  ,slightly hygroscopic powder, very soluble in water, freely soluble in methanol
Therapeutic Category
Antihypertensive
 Chloroquine Phosphate
Active Pharmaceutical Ingredient
Chloroquine Phosphate
Chemical Name
N4-(7-Chloroquinolin-4-yl)N1,N1-diethylpentane-1,4-diamine bis (dihydrogen phosphate)
CAS No.
50-63-5
Molecular Formula
C18H26ClN3.2H3PO4
Molecular Weight
515.86
Pharmacopoeial Compliance
BP / USP / IP / Ph.Eur.
Description
A white or almost white, crystalline powder, hygroscopic. Free soluble in water, very slightly soluble in alcohol and in methanol.
Therapeutic Category
Anti-Malarial
 Chloroquine Sulphate
Active Pharmaceutical Ingredient
Chloroquine Sulphate
Chemical Name
N4-(7-Chloroquinolin-4-yl)N1.N1-diethylpentane-1.4-diaminesulfate
CAS No.
132-73-0
Molecular Formula
C18H26ClN3.H2SO4.H2O
Molecular Weight
436
Pharmacopoeial Compliance
Ph.Eur. / BP / IP
Description
A white or almost white, crystalline powder, freely soluble in water and in methanol, very slightly soluble in ethanol (99.6%),.It melts at about 206°C to 209°C
Therapeutic Category
Anti-Malarial
 Clopidogrel Hydrogen Sulfate
Active Pharmaceutical Ingredient
Clopidogrel hydrogen sulfate
Chemical Name
Methyl (+)-(S)-2-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate, sulfate (1:1)
CAS No.
120202-66-6
Molecular Formula
C16H16ClNO2S.H2SO4
Molecular Weight
419.9
Pharmacopoeial Compliance
USP
Description
White to off-white powder, freely soluble in methanol, practically insoluble in water at neutral pH but freely soluble at pH 1, practically insoluble in ether.
Therapeutic Category
Anti-thrombotic
 Dihydroartemisinin
Active Pharmaceutical Ingredient
Dihydroartemisinin
Chemical Name
3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol
CAS No.
81496-81-3
Molecular Formula
C15H24O5
Molecular Weight
284.4
Pharmacopoeial Compliance
Ph.Int.
Description
Colorless needles or a white or almost white crystalline powder. Practically insoluble in water, slightly soluble in Acetonitrile, Ethanol and Dichloromethane.
Therapeutic Category
Anti-Malarial
 Furosemide
Active Pharmaceutical Ingredient
Furosemide
Chemical Name
4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid
CAS No.
54-31-9
Molecular Formula
C12H11ClN2O5S
Molecular Weight
330.75
Pharmacopoeial Compliance
Ph.Eur. / BP / USP / IP
Description
White to slightly yellow, odourless, crystalline powder. Practically insoluble in water, freely soluble in Acetone, in Dimethyl formamide and in solution of Alkali Hydroxides, soluble in methanol, sparingly soluble in Alcohol, Slightly soluble in ether, very slightly soluble in chloroform.
Therapeutic Category
Diuretic; Antihypertensive
 Hydroxychloroquine Sulphate
Active Pharmaceutical Ingredient
Hydroxychloroquine Sulphate
Chemical Name
Ethanol, 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethyl]amino-, (±)-, sulfate (1:1) (Salt)
CAS No.
747-36-4
Molecular Formula
C18H26ClN3O.H2SO4
Molecular Weight
433.95
Pharmacopoeial Compliance
Ph.Eur. / BP / USP
Description
A White or Practically white crystalline powder. Is odorless and has a bitter taste. Freely soluble in water, Practically insoluble in alcohol, in chloroform and in ether. It melts about 204°C
Therapeutic Category
Anti-Malarial
 Lumefantrine
Active Pharmaceutical Ingredient
Lumefantrine
Chemical Name
2-Dibutylamino-1-[2, 7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]-ethanol(racemate)
CAS No.
82186-77-4
Molecular Formula
C30H32Cl3NO
Molecular Weight
528.94
Pharmacopoeial Compliance
Ph.Int. / USP (Salmos)
Description
A yellow crystalline powder. Practically insoluble in water, soluble in Dichloromethane, Slightly soluble in methanol. Melting range - 128°C to 132°C
Therapeutic Category
Anti-Malarial
 Nimesulide
Active Pharmaceutical Ingredient
Nimesulide
Chemical Name
N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide
CAS No.
51803-78-2
Molecular Formula
C13H12N2O5S
Molecular Weight
308.3
Pharmacopoeial Compliance
Ph.Eur. / BP
Description
Yellow Crystalline powder. Practically insoluble in water, freely soluble in acetone, slightly soluble in anhydrous ethanol. Melts at about 149°C
Therapeutic Category
Anti-inflammatory
 Piperaquine Phosphate
Active Pharmaceutical Ingredient
Piperaquine Phosphate
Chemical Name
1,3-Bis[1-(7-chloro-4-quinolyl)-4'-piperazinyl]propane tetraphosphate tetrahydrate
CAS No.
4085-31-8
Molecular Formula
C29H32Cl2N6.4H3PO4.4H2O
Molecular Weight
999.56
Pharmacopoeial Compliance
IHT
Description
Almost white to light yellow crystalline powder. Melts about 244°C to 252°C
Therapeutic Category
Anti-Malarial
 Pyronaridine Tetraphosphate
Active Pharmaceutical Ingredient
Piperaquine Phosphate
Chemical Name
4[(7-chloro-2-methoxybenzo[b]-1.5-naphthyridine-10-yl)amino]-2.6-bis(1-pyrrolidinyl methyl)phenol tetraphosphate
CAS No.
76748-86-2
Molecular Formula
C29H32ClN5O2.4H3PO4
Molecular Weight
910.03
Pharmacopoeial Compliance
IHT
Description
Yellow amorphous powder, soluble in water, insoluble in methanol and chloroform, melting point 210 oC -214oC
Therapeutic Category
Anti-Malarial
 Tenofovir Disoproxil Fumarate
Active Pharmaceutical Ingredient
Piperaquine Phosphate
Chemical Name
1,1'-bis(1-methylethyl) 1,1'-[({[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl}phosphonoyldioxy)dimethyl] dicarbonate (ester) hydrogen (2E)-but-2-enedioate (salt)
CAS No.
202138-50-9
Molecular Formula
C19H30N5O10P.C4H4O4
Molecular Weight
635.45
Pharmacopoeial Compliance
Ph.Int. / IP
Description
White to almost white crystalline powder, soluble in methanol, slightly soluble in water, very slightly soluble in dichloromethane
Therapeutic Category
Antiretroviral
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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